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EP 58: The Science of Women’s Metabolic Health: Weight Loss, Blood Sugar + Longevity with Dr. Meredith Sweeney

January 21, 2026 Helene Trager-Kusman

EP 58: The Science of Women’s Metabolic Health: Weight Loss, Blood Sugar + Longevity with Dr. Meredith Sweeney

Helene sits down with Dr. Meredith Sweeney, weight loss surgeon turned longevity expert, to break down the real science behind women’s metabolic health, body recomposition and long-term longevity.

Dr. Sweeney explains how women’s hormones impact blood sugar regulation, insulin sensitivity, fat storage and muscle mass. We discuss key differences between women and men and for women at different stages of life when it comes to nutrition and exercise.

If you’ve ever wanted to understand the hype behind CGMs, VO₂ max and other longevity lingo from a women’s perspective, this episode is a breath of fresh air in a male dominated space.

We discuss:

-Metabolic health for women vs. men and for women at different phases of life

-How sleep, stress, nutrition, and exercise impact longevity

-Debunking “calories in, calories out” and the truth about what drives fat loss, insulin resistance and energy balance

-The impact of muscle on insulin and top exercise recs for longevity

-Everything you need to know about CGMs (continuous glucose monitors) and how both Helene and Dr. Sweeney utilize them for long term health

-How to rewire your brain and dopamine pathways to prioritize healthy habits

-Why V02 Max and fasted insulin are the number 1 predictors of longevity and what you can learn from these stats

-A full breakdown on weight loss versus body recomposition and what Dr. Sweeney works on with her patients

-Dr. Sweeney’s journey from bariatric surgery to longevity medicine, plus her powerful IVF story leading to her two sons

-The connection between spirituality and longevity

Listen in for how to improve your metabolic markers, build muscle and rewire your brain for long-term health—without counting calories, obsessing over the scale or forgoing your favorite foods this year!

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Connect with Helene and the Mind Body Mother Community!

Use code PODCAST for 15% off Helene’s 1:1 Integrative Health Coaching

Get 2 months free on your annual Levels membership here

Connect with Dr. Meredith Sweeney here and Sano Longevity here

Learn more about Sano Longevity here

This podcast is for informational purposes only and is not intended to replace professional medical advice.

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EP 58: The Science of Women’s Metabolic Health: Weight Loss, Blood Sugar + Longevity with Dr. Meredith Sweeney
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EP 57: Beat the Winter Blues: Vitamin D, Light Therapy, Cardio, Ayurvedic Nutrition + Nourishing Wellness Habits for Moms





← The Truth About Postpartum Depression, Perinatal Mental Health + Maternal Health Equity with Dr. Karen Sheffield-AbdullahEP 57: Beat the Winter Blues: Vitamin D, Light Therapy, Cardio, Ayurvedic Nutrition + Nourishing Wellness Habits for Moms →

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